2026 Orthopedic Device Industry M&A Roundup (Updated 9/1)

Merger and acquisition (M&A) transactions remain prevalent in the orthopedic device manufacturing industry in many forms—large organizations purchasing smaller, innovative companies and/or businesses, mergers of equals, private equity deals, and orthopedic device contract manufacturers grabbing specialty businesses to round out their offerings.

To help our readers stay up to date about the orthopedic device market’s evolution, ODT will catalog these M&A transactions throughout the year. We hope this will be a helpful resource!

Enovis—eCential Robotics

eCential boasts over 15 years of experience in computer-assisted surgery and orthopedic robotics. Its modular Op.n platform combines surgical navigation and active robotics.
Date of Announcement: September 1, 2026
Value: €155 million
More info

Stryker—ZuriMED

ZuriMED is the privately held developer of the FiberLocker system, which is a novel approach to rotator cuff augmentation with more biomechanical strength to address a key clinical failure mode.
Date of Announcement: August 31, 2026
Value: Not disclosed
More info

Globus Medical—Higgs Boson Health

With a mission to transform healthcare experience through digital innovation, Higgs Boson will position Globus Medical to shape patient and provider experience throughout the full episode of care.
Date of Announcement: Aug. 26, 2026
Value: Not disclosed
More info

Isto Biologics—NovaBone Products LLC

The deal gives Isto Biologics a differentiated portfolio of bioactive glass technologies and expands its ability to support surgeons with a broader range of bone graft options.
Date of Announcement: Aug. 6, 2026
Value: Not disclosed
More info

DePuy Synthes—Expanding Innovations (EI)

Mountain View, California-based EI’s non-screw spinal interbody cage technology is designed to reduce postoperative cage collapse and vertebral body subsidence. Its portfolio includes the X-PAC line of TLIF expandable posterior cages, LLIF expandable lateral cages, and N-GAGE lumbar plates.
Date of Announcement: July 16, 2026
Value: Not disclosed
More info

Biotronik Neuro—Soin Neuroscience

Biotronik acquired spinal cord stimulation intellectual property from Soin Neuroscience, a Dayton, Ohio-based company founded by pain management physician and anesthesiologist Dr. Amol Soin.
Date of Announcement: July 15, 2026
Value: Not disclosed
More info

VB Spine—Augmedics

VB Spine will acquire exclusive rights to Augmedics’ CT-Fluoro augmented reality tool for spine surgery. Using CT-Fluoro, surgeons can register a pre-op scan using standard fluoroscopic imaging.
Date of Announcement: July 7, 2026
Value: Not disclosed
More info

Zimmer Biomet—Pacira Biosciences

Pacira is selling its iovera FDA-cleared, drug-free device that relieves pain using cryoneurolysis, a process where focused cold therapy is applied to a target nerve and temporarily interrupts its ability to transmit pain signals.
Date of Announcement: June 30, 2026
Value: Up to $140 million; $70 million upfront with $70 million more potential milestone payments
More info

EBI—Xstim

Xstim develops next-gen bone growth stimulation solutions, including a modern, wearable, non-invasive spine fusion stimulation therapy.
Date of Announcement: June 18, 2026
Value: Not disclosed
More info

Amplio Spine—FloSpine

Amplio acquired FloSpine’s KeyLift expandable interlaminar stabilization system, a non-pedicle, supplemental fixation device for use at a single level in the non-cervical spine (T1-S1).
Date of Announcement: June 18, 2026
Value: Not disclosed
More info

DePuy Synthes—MinMaxMedical

DePuy Synthes will acquire the company’s in-development Gemtrack radiofrequency (RF) miniature tracker tech for joint reconstruction procedures.
Date of Announcement: May 26, 2026
Value: Not disclosed
More info

Medtronic—SPR Therapeutics

SPR’s FDA-cleared Sprint PNS system is a short-term, 60-day therapy engineered to offer pain relief through a temporary approach that doesn’t require a permanent implant.
Date of Announcement: May 20, 2026 (closed July 16, 2026)
Value: $650 million
More info

Atreon Orthopedics—RenovoDerm

Atreon Orthopedics LLC and RenovoDerm LLC have merged, creating a company that aims to deliver synthetic biomaterials for tissue repair and remodeling. 
Date of Announcement: May 19, 2026
Value: Not disclosed
More info

Bioness—Portable Neuromodulation Stimulator (PoNS) System

Adding the PoNS system expands the company’s platform to include non-invasive neuromodulation delivered via the tongue, stimulating cranial nerve pathways to promote neuroplasticity and functional recovery.
Date of Announcement: April 9, 2026
Value: Not disclosed
More info

Oury Medical Group—Céfiméca

Céfiméca is an orthopedic implant and spinal instrument maker. The transaction represents a new major step in Oury Medical Group’s development and is consistent with the long-term industrial strategy initiated by TAG Partners upon Oury-Guyé’s purchase three years ago.
Date of announcement: April 1, 2026
Value: Not disclosed
More info

Zavation—ChoiceSpine

ChoiceSpine adds a comprehensive portfolio of spinal implant and instrumentation systems spanning cervical, thoracolumbar, and interbody applications.
Date of Announcement: February 26, 2026
Value: Not disclosed
More info

VB Spine—xvision Spine System

VB Spine is acquiring exclusive rights to the xvision Spine System from Augmedics, adding augmented reality (AR) navigation to its enhanced visualization portfolio.
Date of Announcement: February 16, 2026 (closed April 13, 2026)
Value: Not disclosed
More info

VB Spine—Robotron Surgical Technologies

VB Spine will acquire Robotron’s SpineHawk platform, adding intraoperative spinal visualization and a software roadmap to support tech-enabled spine care.
Date of Announcement: January 15, 2026
Value: Not disclosed
More info

Tecomet—Orchid Orthopedic Solutions

The companies began an agreement to merge, combining complementary capabilities to better serve customers, expand reach, and support long-term growth.
Date of Announcement: January 14, 2026 (closed May 14, 2026)
Value: Not disclosed
More info

Smith+Nephew—Integrity Orthopaedics

Integrity is the early-stage developer of Tendon Seam, a rotator cuff repair system designed to reduce re-tear rates and improve outcomes.
Date of Announcement: January 12, 2026
Value: $225 million upfront, up to an additional $225 million in performance-based payments
More info

VB Spine—Stryker

VB Spine completed the acquisition of Stryker’s spine implant manufacturing facility in Cestas, France.
Date of Announcement: January 6, 2026
Value: Not disclosed
More info

Year-by-Year

2025 Orthopedic Device Companies M&A Roundup
2024 Orthopedic Device M&A Roundup